A brainstem lesion of any type that involves the medial longitudinal fasciculus (MLF) can cause internuclear ophthalmoplegia (INO). This primarily affects conjugate horizontal gaze and classically manifests as impaired adduction ipsilateral to the lesion and abduction nystagmus contralateral to the lesion. Here, we describe the anatomy of the
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Oct 12, 2014 · Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) is a syndrome describing a disorder of ocular motility that encompasses the following clinical signs: bilateral adduction deficits, bilateral abducting nystagmus, and a large angle exotropia in primary gaze. 1 Several systemic conditions such as multiple sclerosis (MS) have been associated with either unilateral or bilateral
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